Monika Engelhardt Selected Research

Cyclin B

1/2021	Targeting mitotic exit in solid tumors.
12/2013	BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy.
1/2013	The 3' untranslated region of the cyclin B mRNA is not sufficient to enhance the synthesis of cyclin B during a mitotic block in human cells.

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Monika Engelhardt Research Topics

Disease

62	Multiple Myeloma 11/2022 - 02/2006
17	Neoplasms (Cancer) 11/2022 - 08/2007
6	Anemia 11/2022 - 10/2015
5	Infections 02/2022 - 10/2013
5	Lymphoma (Lymphomas) 01/2022 - 08/2007
5	Primary Myelofibrosis (Myelosclerosis) 11/2020 - 01/2014
5	Immunoglobulin Light-chain Amyloidosis 01/2019 - 04/2013
4	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 06/2012
4	Paraproteinemias (Monoclonal Gammopathy) 01/2021 - 05/2006
3	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2021 - 06/2012
3	Hematologic Neoplasms (Hematological Malignancy) 11/2021 - 01/2013
3	Lung Neoplasms (Lung Cancer) 01/2021 - 01/2014
3	COVID-19 11/2020 - 01/2020
3	Frailty 01/2020 - 01/2016
3	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2018 - 01/2014
2	Genomic Instability 01/2022 - 01/2016
2	Chromosome Aberrations (Chromosome Abnormalities) 01/2022 - 06/2012
2	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2003
2	Thrombocytopenia (Thrombopenia) 01/2021 - 01/2018
2	Smoldering Multiple Myeloma 01/2021 - 03/2016
2	Fatigue 01/2021 - 11/2009
2	Polycythemia Vera 11/2020 - 01/2018
2	Sarcoma (Soft Tissue Sarcoma) 01/2018 - 01/2014
2	Disease Progression 01/2018 - 03/2016
2	Splenomegaly 01/2018 - 01/2014
2	Plasmacytoma 01/2017 - 08/2007
2	Monoclonal Gammopathy of Undetermined Significance 03/2016 - 06/2014
2	Bone Diseases (Bone Disease) 10/2015 - 06/2012
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 10/2012 - 04/2005
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 06/2012 - 10/2005
1	Prostatic Neoplasms (Prostate Cancer) 11/2022
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022
1	Hypercalcemia (Milk Alkali Syndrome) 08/2021
1	Hemolysis 01/2021
1	Thrombotic Microangiopathies 01/2021
1	Acute Kidney Injury (Acute Renal Failure) 01/2021
1	Human Influenza (Influenza) 01/2021
1	Hemolytic Anemia 11/2020

Drug/Important Bio-Agent (IBA)

15	Bortezomib (Velcade)FDA Link 01/2022 - 08/2007
11	Dexamethasone (Maxidex)FDA LinkGeneric 01/2022 - 08/2007
10	Lenalidomide (CC 5013)FDA Link 01/2022 - 02/2012
7	carfilzomibIBA 01/2021 - 09/2017
6	Proteasome InhibitorsIBA 01/2021 - 09/2017
6	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2003
5	pomalidomideIBA 01/2022 - 01/2014
3	LigandsIBA 11/2022 - 08/2007
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 08/2007
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2021 - 10/2018
3	Antimitotic AgentsIBA 01/2021 - 01/2013
3	Cyclin BIBA 01/2021 - 01/2013
3	Immunomodulating AgentsIBA 01/2018 - 09/2017
3	Diphosphonates (Bisphosphonates)IBA 02/2017 - 06/2012
3	Immunoglobulin G (IgG)IBA 10/2015 - 11/2009
2	Hemoglobins (Hemoglobin)IBA 11/2022 - 10/2015
2	Immunoglobulins (Immunoglobulin)IBA 02/2022 - 03/2016
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2022 - 01/2021
2	UbiquitinIBA 01/2022 - 01/2021
2	Melphalan (Alkeran)FDA LinkGeneric 11/2021 - 03/2018
2	selinexorIBA 09/2021 - 01/2019
2	ParaproteinsIBA 08/2021 - 11/2017
2	Anaphase-Promoting Complex-CyclosomeIBA 01/2021 - 12/2013
2	Thalidomide (Thalomid)FDA Link 01/2021 - 09/2017
2	venetoclaxIBA 01/2021 - 01/2020
2	Bendamustine Hydrochloride FDA Link 01/2021 - 10/2012
2	Monoclonal AntibodiesIBA 05/2020 - 01/2018
2	DiureticsIBA 01/2019 - 08/2002
2	ruxolitinibIBA 01/2018 - 01/2014
2	Rituximab (Mabthera)FDA Link 01/2017 - 10/2012
2	Methotrexate (Mexate)FDA LinkGeneric 01/2017 - 06/2012
2	Biological ProductsIBA 07/2016 - 06/2014
2	Pharmaceutical PreparationsIBA 10/2015 - 10/2013
2	Caspofungin (Cancidas)FDA Link 02/2015 - 09/2012
2	posaconazole FDA Link 10/2013 - 09/2012
1	Prostate-Specific Antigen (Semenogelase)IBA 11/2022
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022
1	CyclinsIBA 01/2022
1	VaccinesIBA 12/2021
1	PENTAIBA 09/2021
1	Taxoids (Taxanes)IBA 01/2021
1	Chimeric Antigen ReceptorsIBA 01/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2021
1	eculizumab FDA Link 01/2021
1	daratumumabIBA 01/2021
1	Ligases (Synthetase)IBA 01/2021
1	Decitabine FDA Link 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Etoposide (VP 16)FDA LinkGeneric 01/2021
1	Dapsone FDA Link 11/2020

Therapy/Procedure

32	Therapeutics 02/2022 - 08/2007
11	Stem Cell Transplantation 01/2022 - 02/2006
6	Drug Therapy (Chemotherapy) 11/2021 - 03/2006
4	Homologous Transplantation 11/2019 - 02/2012
3	Hematopoietic Stem Cell Transplantation 12/2021 - 01/2018
3	Blood Component Removal (Apheresis) 01/2021 - 01/2017
2	Precision Medicine 11/2022 - 01/2020
2	Transplantation 01/2021 - 06/2012
2	Immunotherapy 01/2018 - 01/2017
2	Cell Transplantation 01/2016 - 06/2012
2	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 11/2007 - 03/2006
1	Length of Stay 01/2021